Free Shipping on orders over 50$

British Pound Sterling - GBP Euro - EUR US Dollar - USD (EUR)

Welcom to Gentaur Biotech Products!

ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 2 (STEAP2)

Be the first to review this product

Availability: In stock


Quick Overview

[#E97122Hu] ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 2 (STEAP2)


E97122Hu | ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 2 (STEAP2), 96T/Kit
More informations about ELISA Kit for Six Transmembrane Epithelial Antigen Of The Prostate 2 (STEAP2) in

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

(1) The possible impact of hyperuricemia on serum soluble receptor for advanced glycation end products (sRAGE) levels in teenagers: a case control study.[TOP]

Pubmed ID :30101695
Publication Date : //
Background Dietary advanced glycation end products (AGEs) and their interactions with the soluble receptors for AGEs (RAGE) play a crucial role in the pathogenesis of cardiovascular diseases. Objective This study was set out to assess, whether there was any association between serum sRAGE level and serum uric acid level in children with hyperuricemia Methods This case control study involved 53 patients (12 girls, 41 boys) with hyperuricemia (defined as serum uric acid >4.8 and >5.5 mg/dl in girls and boys, respectively) aged median of 13.5-15.5 years. Thirty-six healthy individuals with normal serum uric acid level were selected as a reference group. Additionally the study group with hyperuricemia was divided into two groups: HU-HT (hypertensive n=25) and HU-NT (normotensive n=28) teenagers. The serum concentration of human sRAGE was measured using a commercially available enzyme-linked immunosorbent assay (ELISA) kit. Results We found statistically significant differences in serum sRAGE levels between normotensive subjects with hyperuricemia median: 169.8 pg/ml (Q1-Q3:148.3-231.1 pg/ml) and reference group median: 129 pg/ml (Q1-Q3:107.4-175.3 pg/ml), p<0.01. Univariate analysis of the data revealed positive correlation between serum sRAGE and serum uric acid (r=0.306, p<0.05). Conclusion Our data showed that adolescents with an increased serum uric acid level had higher serum sRAGE levels. One of the possible explanation is of the oxidative stress, which plays an important role in pathogenesis of inflammation in patients with hyperuricemia. A question arises whether serum sRAGE might be a sensitive marker of inflammation process caused by hyperuricemia. Further studies are required to assess the relationship between sRAGE and markers of endothelial dysfunction.

Authors : Lemiesz M, Tenderenda-Banasiuk E, Sosnowska D, Rybi-Szuminska A, Storonowicz J, Lemiesz T, Wasilewska A,

(2) The effect of NAD-299 and TCB-2 on learning and memory, hippocampal BDNF levels and amyloid plaques in Streptozotocin-induced memory deficits in male rats.[TOP]

Pubmed ID :30027497
Publication Date : //
Alzheimer's disease (AD) is the most common form of dementia characterized by a progressive decline in cognitive function. The serotonergic system via the 5-HT1A receptor and 5-HT2A receptor is proposed to affect the cognitive process.

Authors : Afshar Simin, Shahidi Siamak, Rohani Ali Haeri, Komaki Alireza, Asl Sara Soleimani,

(3) Reflection and observation: cell-based screening failing to detect HBV in HUMSCs derived from HBV-infected mothers underscores the importance of more stringent donor eligibility to reduce risk of transmission of infectious diseases for stem cell-based medical products.[TOP]

Pubmed ID :29973264
Publication Date : //
In cell-based therapy, the transmission of communicable diseases imposes a substantial threat to recipients. In this study, we investigated whether cell-based screening could detect hepatitis B virus (HBV) in human umbilical cord-derived mesenchymal stem cells (HUMSCs) isolated from HBV-infected donors to understand the susceptibility of HUMSCs to HBV infection.

Authors : Liu Wei, Xie Yuanyuan, Gao Tianyun, Huang Feifei, Wang Liudi, Ding Lijun, Wang Wenqing, Liu Shuo, Dai Jianwu, Wang Bin,

(4) Detection of pregnancy in sheep using an ELISA for pregnancy-specific protein B.[TOP]

Pubmed ID :29958526
Publication Date : //
The early detection of pregnancy and the determination of fetal numbers have economic benefits in sheep production because of the seasonal breeding patterns where missing a breeding opportunity means the loss of one productive year. The purpose of this study was to evaluate the efficacy of the B6-HRP ELISA for ovine pregnancy-specific protein B (oPSPB) measurement in the detection of pregnancy and estimation of fetal numbers in different sheep breeds. BioPRYN® ELISA assay kit was used for the detection of pregnancy in the experimental animals. Ninety-three ewes of three breeds (British Milksheep - BM, Lacaune - L and Transylvanian Racka - TR), each from three farms in Hungary, were included in the study. BM and L ewes were artificially inseminated (AI). Thirty-five days after AI, all ewes were examined by transabdominal ultrasound. The TR flock was mated naturally over a six-week period. At the end of the mating period, the ewes were similarly examined by ultrasound. Blood samples were taken from all pregnant ewes twice (35 and 65 days after AI), and serum samples were assayed by the BioPRYN test. It can be concluded that the detection of serum PSPB by ELISA is a much easier, safer, less expensive and highly accurate method for the detection of ovine pregnancy. Although some breed-related differences were detectable at 35 and 65 days post breeding, no differences in oPSPB levels were found in pregnant ewes carrying different numbers of fetuses.

Authors : Milisits-Németh Tímea, Balogh Orsolya Gabriella, Egerszegi István, Kern László, Sasser R Garth, Gábor György,

(5) [Seroprevalence of pertussis toxin antibody in Manisa province of Turkey, after six years implementation of acellular pertussis vaccine].[TOP]

Pubmed ID :29933735
Publication Date : //
Vaccination is the most effective way of preventing pertussis disease. Turkey commenced a routine infant immunization program using whole cell (wP) pertussis vaccine in 1968. Immunization accelerated in 1985 after participation of Turkey in the Expanded Programme on Immunization initiated by the World Health Organization. Acellular vaccine (aP) replaced wP in 2008 and a booster was added to age 6 in 2010. The immunization programme was successful in reducing the morbidity rate from 20.58 per 100.000 in 1970 to the lowest level of 0.01 per 100.000 in 2009. However, reduction of vaccine-induced protection and reduced natural boosting of circulating Bordetella pertussis are likely to increase the susceptibility of the population. As a result, morbidity rate increased from 0.09 per 100.000 to 0.41 per 100.000 in 2015 compared to the previous year. The aim of this epidemiological study was to determine the seroprevalence of pertussis toxin (PT) antibodies among healthy people and its association with various social determinants in Manisa province in Turkey, 6 years after aP replaced wP vaccine. The study was conducted as a cross-sectional study with a sample of 1250 people that was randomly selected from the over 2 years of age population in Manisa in 2014. Seroprevalence of PT antibody was determined as the dependent variable of the study. Independent variables of the study were; gender, age, migration in the last 5 years, occupational class, perceived income, house ownership, number of people per room, annually per capita equivalent income. The presence of anti-PT IgG was detected by quantitatively using a commercially available ELISA kit. The antibody levels were categorized into groups according to pertussis infection or vaccination immune response status. The groups consisted of undetectable (< 5 IU/ml), mid-range (5-< 62.5 IU/ml: more than one year previously), high (62.5-< 125: with in 12 months) and very high (≥ 125 IU/ml: with in 6 months) antibody levels. The test results with ≥ 5 IU/ml were defined as seropositive. Level > 100 IU/ml detected among adolescent and adult participants indicated acute or recently recovered pertussis infection. Chi-square test was used to evaluate association between social determinants and pertussis seropositivity. The seroprevalence of the whole study population was 58.1% (95% CI 55.32-60.79) and no association was found with any of the social determinants. The highest seroprevalence was found among 2-9 age group (68.3%) followed by 70-79 age group (63.5%). The lowest seroprevalence was found among 20-29 age group (50.9%) followed by 10-19 age group (51.6%). When seropositivity levels according to ages were compared, it was found that there was a decrease one year after the first vaccination at 2nd, 4th and 6th months and the booster at the 6th year, with a lowest rate (19%) in 11 year-old. The highest seropositivity (77.3%) with a level of >100 IU/ml (13.6%) were detected at age 15 among all adolescent and adult participants. Adding an adolescent booster to immunization schedule and recommendation of vaccine to elderly people should be considered to reduce the incidence of pertussis disease in Turkey.

Authors : Özbek Özgen Alpay, Öktem İbrahim Mehmet Ali, Hekimoğlu Can Hüseyin, Sekreter Özgür, Emek Mestan, Atasoylu Gonca, Açıkgöz Ayla, Demirpençe Nur, Ceylan Ali, Baykal Elif Sanem, Ünal Belgin,

(6) Prevalence of Antibody against Angiotensin II Type 1 Receptor (AT1R) Among Thai Kidney Transplant Patients.[TOP]

Pubmed ID :29880351
Publication Date : //
Non-HLA antibodies specific to angiotensin II type 1 receptor (AT1R-Ab) are associated with antibody-mediated rejection after kidney transplantation. This study aimed to determine the prevalence of AT1R-Ab among pre-transplantation Thai patients and to compare the association of patient demographics with AT1R-Ab levels.

Authors : Viboon S, Townamchai N, Phiancharoen S, Kupatawintu P, Dhitivat V, Nathalang O,

(7) A new kit to detect Campylobacter species in stool specimens: the Orion GenRead Campylobacter®.[TOP]

Pubmed ID :29862421
Publication Date : //
Campylobacter enteritis is the most frequent bacterial enteritis including in children. Its diagnosis suffers from the lack of sensitivity and delayed result of culture. Our aim was to test a new PCR-derived method for Campylobacter diagnosis in comparison to a composite reference. Patients presenting to the emergency ward of our hospital with enteric symptoms during the 2016 summer season were included. In addition to culture, an ELISA and an in-house real-time PCR were performed, as well as the new method (Orion GenRead Campylobacter) on all stool specimens. The composite reference used to consider a case positive for Campylobacter was either culture positive and in case of negative culture both the ELISA and real-time PCR positive. One hundred fifty patients were included, 64 being infants or children. There were 29 cases positive by the composite reference, with 19 of the 64 children (29.7%) and 10 of the 86 adults (11.6%). If performed alone, culture would have missed six cases. The Orion GenRead Campylobacter detected all the positives by the composite reference but also 12 cases negative by the composite reference (sensitivity 100%, specificity 90.1%). Given the characteristics of the new method, it can be used as a screening method for Campylobacter detection.

Authors : Buissonnière Alice, Bénéjat Lucie, Charron Paul, Bessède Emilie, Lehours Philippe, Valdenaire Guillaume, Richer Olivier, Mégraud Francis,

(8) An Enzyme Immunoassay for Determining Immunoreactive Trypsinogen (IRT) in Dried Blood Spots on Filter Paper Using an Ultra-Microanalytical System.[TOP]

Pubmed ID :29808455
Publication Date : //
Cystic fibrosis (CF) is a severe autosomal recessive disorder. It is caused by mutations in the CF transmembrane conductance regulator gene. Early diagnosis of CF can be carried out by determining high immunoreactive trypsinogen (IRT) blood values in newborns. A simple sandwich-type ultramicroELISA assay (UMELISA®) has been developed for the measurement of IRT in dried blood spots on filter paper. Strips coated with a high affinity monoclonal antibody directed against IRT are used as solid phase, to ensure the specificity of the assay. The assay is carried out within 20 h. The useful rank of the curve is 0-500 ng/mL, and the lowest detectable concentration is 4.8 ng/mL. Intra- and inter-assay coefficients of variation were lower than 10%. The recovery mean value was 100.3 ± 11.2%. Cross-reactivity with proteins structurally related to IRT (α2-macroglobulin, α1-antitrypsin, and human chymotrypsin) was lower than the detection limit of the assay. Four thousand four hundred six newborn samples from the Cuban Newborn Screening Program were analyzed, and the mean IRT concentration was 12.8 ng/mL. Higher IRT values were obtained when samples were eluted overnight. Regression analysis showed a good correlation with the commercially available AutoDELFIA® Neonatal IRT kit (n = 3948, r = 0.885, ƙ = 0.976, p < 0.01). The analytical performance characteristics of our UMELISA® TIR Neonatal suggest that it can be used for the neonatal screening of CF.

Authors : Castells Martínez Elisa M, González Ernesto Carlos, Tejeda Yileidis, Frómeta Amarilys, Martín Odalys, Espinosa Maryeris, Del Río Lesley, Pérez Pedro L, Morejón Greilys, Perea Yenitse, Melchor Antonio,

(9) [Effect of vascular endothelial growth factor 165-loaded porous poly (ε-caprolactone) scaffolds on the osteogenic differentiation of adipose-derived stem cells].[TOP]

Pubmed ID :29806274
Publication Date : //
To explore the effect of vascular endothelial growth factor 165 (VEGF )-loaded porous poly (ε-caprolactone) (PCL) scaffolds on the osteogenic differentiation of adipose-derived stem cells (ADSCs).

Authors : Xu Wanlin, Lu Hao, Ye Jinhai, Yang Wenjun,

(10) Bisphenol A-Induced Endocrinotoxicity and Male Reprotoxicopathy is Modulated by the Dietary Iron Deficiency.[TOP]

Pubmed ID :29779488
Publication Date : //
Bisphenol A (BPA) is suspected to cause hormonal imbalance in humans. Dietary factors are known to bring changes in hormonal profile. In order to study chemico-biological interaction of iron deficiency on toxicity outcome of BPA exposure, we studied the modulatory effects of iron deficiency on the hormone levels in rats chronically-exposed to BPA.

Authors : Rashid Hina, Sharma Shikha, Beigh Saba, Ahmad Firoz, Raisuddin Sheikh,